Further nuclease stabilization is achieved by substitution of 2?-OCHstep step 3 for 2?-OH at purine positions. As the 2?-OCH3 moiety is not compatible with current SELEX process enzymes, this alteration must occur during chemical synthesis following evolution of a specific aptamer sequence. Generally, most of the 2?-OH purines can be substituted without loss of binding…
Call us NOW!!: 704-208-4126
2014 © Copyright - Tax & Business Resources LLC.TBR Charlotte by Smash